Thursday, January 20, 2011

Mount Sinai School of Medicine, HDL, and LDL

Because quite a few of you don't really know yet where I study and what I'll be working on, here a short overview:
I work in the Nanomedicine lab at the Translational and Molecular Imaging Institute of the Mount Sinai School of Medicine. (Just for your information: this year Mount Sinai ranks 18th world wide for best medical schools ;)).
In this six months I will learn how to make HDL-like nanoparticles (NPs). When I know how to work with these NPs, I will try to make LDL-like NPs, which is more complicated because the Apo-B1 isolation is tricky (whereas the Apo-A1 for HDL is easy to handle). But guess I will find out! I know, most of you have no idea what I am talking about, you could do a google search, or just trust me: HDL = good and has atherosclerosis protective properties, where LDL = bad. The NPs we make that mimic HDL or LDL will carry an iron oxide (FeO) in their core, so whe can image the NPs with, among others, MRI and TEM. Sounds interesting, don't you think? Well, I am really excited about the project :)!

Today was the second day in the lab here, and I think I got pretty used to it now. And the same with the building, I think today was the first day I didn't get lost! Because of reconstructions, our offices are now at the "Autopsy Suite". I still have to get used to it, and it seems more people have: Last Monday I was in, and one of the security guards asked me what I was doing there, and he had to check my bag. I think I have to get used to that, because these guards always tend to ask who you are and where you are going.

I have no pictures yet of Mount Sinai, I will try to make some when the guards are not paying attention!

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